Sunday, August 19, 2012

Diagnosing and Managing Tetanus and Botulism in Horses




  Tetanus and botulism are two diagnoses horse owners never want to receive, both of these equine illnesses are known for moderate to high fatality rates. But fortunately, owners can protect their horses from these diseases by staying up-     to-date with annual vaccinations.
                                     During a presentation at the 2012 American College of Veterinary Internal Medicine Forum, held May 30-June 2 in New Orleans, La., Allison Stewart, BVSc (Hons), MS, Dipl. ACVIM, ACVECC, associate professor of equine internal medicine at Auburn University, lectured on diagnosing and managing both tetanus and botulism.
Tetanus
An often fatal disease, tetanus (also called lockjaw) is caused by toxins released by Clostridium tetani, a bacterium that Stewart explained lives in soil, especially in areas with feces present. Horses generally contract tetanus via wound contamination with affected soil.
Stewart said that clinical signs typically take two to four weeks to develop after infection and include:
  • A stiff gait;
  • A "sawhorse" stance, in which the front legs are extended out in front of the horse and the back legs are positioned further out from the back of the horse;
  • Prolapsed third eyelid;
  • Flared nostrils;
  • Retracted lips;
  • Perked ears;
  • Exaggerated response to stimuli; and
  • Respiratory paralysis.
Veterinarians generally diagnose the disease based on clinical signs and rarely require a culture confirmation, she said.
When caring for an affected horse, Stewart recommended the following treatment protocol:
  • Place the horse in a quiet, nonstimulating environment (such as a dark stall), and consider plugging his ears to reduce external stimuli;
  • Provide deep bedding or, if necessary and tolerated, a sling;
  • Administer sedatives and muscle relaxers to keep the patient as quiet and comfortable as possible;
  • Identify any wounds or hoof abscesses and ensure they are well-drained and have good oxygen exposure;
  • Treat wound infections with the antibiotic metronidazole;
  • Administer antitoxin as soon as tetanus is suspected; and
  • Make use of parenteral (intravenous) nutrition and intravenous electrolytes or feeding and watering via a nasogastric tube.
"The prognosis is good if 1) the horse can still drink; 2) the horse remains standing (there's an 80% mortality rate if recumbent); and 3) the horse survives more than one week after the onset of signs," Stewart said.
Although fatality rates for tetanus can reach as high as 50% to 75%, there is some good news: Tetanus is largely preventable, and an antitoxin can be effective if administered early in the disease process.
"Although horses are traditionally vaccinated with tetanus toxoid each year, protection is probably longer lasting," Stewart said. "The vaccine is cheap and effective and the best insurance you can ever buy for your horse. There is no excuse not to vaccinate horses, but in an emergency an antitoxin can be given to horses to provide very rapid, but short-lasting immunity to the toxin produced by C. tetani."
For horses without a vaccination history or not previously vaccinated against tetanus, Stewart recommends prophylaxis (disease prevention) if wounds are sustained. She recommended administering 1,500 IU of tetanus antitoxin and simultaneous vaccination with tetanus toxoid.
Botulism
Switching gears, Stewart turned her attention to diagnosing and managing botulism, an often fatal disease that affects horses of all ages.
"Botulism is caused by a toxin produced by C. botulinum," she explained. "Eight types of toxin--A, B, Ca, Cb, D, E, F, and G--have been recognized," with type B being associated with the majority of equine botulism cases each year.
Stewart said there are three ways horses can contract botulism:
  • Toxin ingestion (via contaminated forage);
  • Wound contamination; and
  • Toxicoinfections (also known as shaker foal syndrome, this form occurs in foals when spores are consumed, germinate, and are absorbed by the gastrointestinal tract).
Clinical signs of botulism typically arise three to seven days after infection and include:
  • Dysphagia (the inability to swallow);
  • Progressive muscle paralysis;
  • Restlessness;
  • Incoordination (ataxia);
  • Inability to stand or shaking as they stand up;
  • Lateral recumbency;
  • Decreased tongue and tail tone.
  • Veterinarians generally diagnose the disease via clinical signs and identifying the toxin in feces, serum, or other tissue, she said.
  • Treatment includes:
  • Multivalent (multi-strain) antiserum administration;
  • Movement restriction;
  • Ventilation or oxygen therapy, if needed;
  • Antibiotics for secondary complications;
  • Cathartic (a purging medication) administration;
  • Parasympathomimentic drug (which stimulates or mimics the parasympathetic nervous system) administration; and
  • Supportive care.
As with tetanus, botulism caused by C. botulinum type B is largely preventable via vaccination administration, Stewart said. There are not yet vaccines available to protect against the other types, she noted.
"To prevent shaker foals, vaccinate the mare three times at monthly intervals (with the last dose coming) two to three weeks before foaling," she recommended. During subsequent pregnancies she suggested a single injection during the last month.
Learn more about the importance of nutrition, vaccinations, and deworming programs designed to keep your horse healthy in Understanding Equine Preventive Medicine.
"For the protection of adults, (administer) yearly vaccinations after the initial series of three doses," she said.
Take-Home Message
Both tetanus and botulism can be fatal if contracted, but annual vaccination reduces horses' risk of contracting. Discuss individual vaccine recommendations if questions arise about a particular anima

COURTESY: To  "THE HORSE " & Editor

Wednesday, August 15, 2012

The Truth About Internet Vets Inbox x

You can find almost anything on the Internet these days. In the space of 2 short decades it has gone from a relatively uncommon technology to being considered a necessity for many people. You can find information on almost anything online. In just a few minutes you can learn about current events, entertainment, history, hobbies, and yes…even pet health.

But just because something is online doesn't make it true. It's easy for anyone to put information out there and when it pertains to our pets it doesn't take long for that false information to become dangerous. For example, today I met a family with a tortoise who was very ill. It turns out that they were feeding him the wrong diet and he was very malnourished as a result. When I asked them where they got their care information they told me that they found it online. Oh dear! (Don't worry, the little tortoise is on a better diet now and his family now knows much more about caring for him. It will take some time but he is on his way to recovery.)

This made me appreciate just how wonderful all of the PetPlace.com vets are. Every single one of the articles on Pet Place is vet-approved, so that means that they are assessed for accuracy before we ever put them on the website. And every person who works for Pet Place is a pet lover themselves so we really care about “getting it right.” It's our mission to help you give your pets the very best care and the longest life possible.

Did you know that PetPlace.com has over 10,000 vet-approved articles for you to read? They cover everything from cat nutrition to dog breeding and even yes…tortoise care. And with so many articles to read we even have a handy search bar as well as sections for popular subjects. Best of all, it's all FREE!

If you haven't looked around our website lately, I strongly encourage you to do so. There's so much to see and I guarantee you will learn something! Drop by PetPlace today and see what's new.
For Tamil Go to: கால்நடை மருத்துவர் பக்கம்

When is My Dog Considered a Senior?

At some point in your time as a dog lover you have probably come across the term “senior.” You might even be preparing for your own dog to enter their golden years, or have a dog who already qualifies as a senior. Many dog lovers have an idea of what being “senior” entails but aren't quite sure if their dog is there yet.

Part of determining whether your dog fits into this category is their age. When is the cut-off point? Well, there are two answers, a simple and a complex one. In the simplest terms veterinarians typically consider the last 25% of a dog's life to be their senior years. The more accurate but more complex answer is based on your dog's breed. Different breeds have different life expectancies and might age slightly differently. The following article offers a handy list of life expectancies according to breed. Please remember that these are just general guidelines and that many factors can affect your dog's health. Furthermore, if your dog is a mixed breed you can consider the expectancies of both of them.
For Tamil Go to: கால்நடை மருத்துவர் பக்கம்
To see the list of expectancies by breed, go to: When is Your Dog Considered a Senior?


No matter your dog's age, I know you will give them the best care and lots of love. Senior dogs are such a joy - consider yourself lucky if you share your life with one!Having an older pet can mean you need to make special considerations for their health. For tips on giving them the best care, go to: Keeping Your Dog Healthy

WOOF! WOOF! - What Are Our Dogs Saying to Each Other?

It's not uncommon for two strange dogs to meet and either become fast friends or the biggest enemies within seconds. How does that happen? It's all about the little signals passed between dogs as they communicate.

Canine communication is just as important with dogs who know each other as it is with dogs who have just met. The sweetest, gentlest dogs might get frustrated and show some signals of irritation too. Or maybe you have a shy dog who hides from everything…until he or she meets that special friend that brings out their playful side. What are our dogs saying to each other?

Well, the answer is pretty complex, but I'd like to share an article that's a good place to start. It is an excellent insight into the way that your dog communicates with other members of its species. Go to: Dog to Dog Communication

Friday, August 10, 2012

Dogs and Cats - Epilepsy A Homeopathic approach


Dogs and Cats - Epilepsy A Homeopathic approach





       The first problem to overcome in treating epilepsy is the fact that we are dealing with a condition that, in most cases, has very violent symptoms. The salivation, muscular spasms, sometimes involuntary howling that can occur, together with the in-coordination of the recovery period, produce an understandable state of revulsion in many owners, compounded by a feeling of helplessness, especially when they witness it for the first time. This has two consequences with regard to treatment. The first is that there can be an undue concentration on the presenting symptom rather than on the whole picture, and an undue emphasis in treatment on preventing further fits at any price. Hahnemann laid great stress on the fact that disease can only be cured “if the physician clearly perceives what has to be cured… in each individual case of disease”, and this applies to epilepsy just as much as to any other condition. True epilepsy is not an acute condition but is part of a chronic disease pattern, in many instances what Hahnemann referred to as a “one-sided disease”. The really successful approach to its treatment is constitutional. The second consequence is that accurate observation and reporting of the exact symptoms of a fit can be difficult. In one sense this is not as important as it may seem, as many of the features are local or common symptoms, but useful information can be obtained from this area of the picture. Another factor affecting the disease picture is that many cases that …

The first problem to overcome in treating epilepsy is the fact that we are dealing with a condition that, in most cases, has very violent symptoms. The salivation, muscular spasms, sometimes involuntary howling that can occur, together with the in-coordination of the recovery period, produce an understandable state of revulsion in many owners, compounded by a feeling of helplessness, especially when they witness it for the first time. This has two consequences with regard to treatment. The first is that there can be an undue concentration on the presenting symptom rather than on the whole picture, and an undue emphasis in treatment on preventing further fits at any price.

Hahnemann laid great stress on the fact that disease can only be cured “if the physician clearly perceives what has to be cured… in each individual case of disease”, and this applies to epilepsy just as much as to any other condition. True epilepsy is not an acute condition but is part of a chronic disease pattern, in many instances what Hahnemann referred to as a “one-sided disease”. The really successful approach to its treatment is constitutional.

The second consequence is that accurate observation and reporting of the exact symptoms of a fit can be difficult. In one sense this is not as important as it may seem, as many of the features are local or common symptoms, but useful information can be obtained from this area of the picture.

Another factor affecting the disease picture is that many cases that present for homeopathic treatment are already receiving conventional anticonvulsant drugs. These may be failing to control the situation adequately and/or there may be concerns over the side effects of their long-term use. One of the commonest drugs used is phenobarbitone and one of the other standard medications, Mysoline, is broken down in the body into barbiturate. Long-term use of these agents can pose a strain on the liver. In addition, from the homeopathic point of view, this approach represents a degree of suppression of the case, with all the problems that that implies. However, in spite of this it cannot be stressed too strongly that such treatments must not be withdrawn suddenly, and any changes must take place under veterinary supervision. However, homeopathy right from the start gives the best chance of cure.

More cases of epilepsy are seen in dogs than in cats. Cats, unlike dogs, are a species that cannot synthesize the amino acid Taurine and hence, care is taken to add it to their diet. One of the effects of Taurine in the body is as a controller of nervous impulses, and supplementing the diet of dogs to give higher levels can raise the threshold at which fits are triggered. Although not homeopathic, its use can be beneficial in the overall management of a case. Other ways of reducing the susceptibility to fits involves the use of herbal preparations, which can be helpful on occasions.

In some ways the cases where there is complete control of the fits by conventional medication are the most difficult. The picture is distorted and also the assessment of progress following a remedy is extremely difficult. Other changes in the body, usually behavioral, may give an indication of some action by the remedy, but a reduction of the medication is often the only way of ascertaining any beneficial effect. In contrast, those cases where there are still some fits occurring, do offer a yardstick by which to judge progress.

Because we are dealing with a chronic disease, often treatment will throw up symptoms in other areas as the whole case is revealed. The major systems that are associated are the skin and the bowels, and there may be a “see-saw” between the symptoms.

The question of potency is an important consideration when prescribing the constitutional remedy. This is one of those conditions where the last thing we want is an aggravation! Hence caution is advisable and more moderate potencies are often initially employed, even in those cases where the indications for a particular remedy are strong. Of course in any acute episode where a remedy is being used to control a fit, then high potencies are very useful, as there is a high-energy output from the condition at that time.

The causes of epilepsy are many and it would not be appropriate here to consider all the factors that can possibly be linked, but one in particular is worthy of mention. That is vaccination. It is well documented that vaccinations, both primary and boosters, can on occasion produce convulsions. No animal with a history of convulsions, from whatever cause, should be given a vaccination without very good reason. Silica, having both convulsions and “ailments from vaccination” in its picture is extremely useful here.

Homeopathic treatment falls into two types. One is the full constitutional approach, aimed at obtaining a complete cure, as this offers the best hope of success. Sometimes an “acute” remedy is used in addition. The other involves a compromise, with the use of both homeopathic and conventional medications. The aim here is to use homeopathy to reduce the dependence on heavy medication, thereby increasing the safety margins and improving the quality of life for the patient.
Case Histories

Coco was a four-year-old golden retriever. She had had several fits over the previous three years, but these had been fairly mild and “very occasional”, with a quick recovery. No conventional treatment had been given as the fits were mild and infrequent. However, the latest two fits had been more severe and frequent, and although apparently recovered, she now appeared “not quite her usual self”. The fits had lasted about five minutes. There was no incontinence or howling, just a general spasm of the whole body with the head thrown back over the right shoulder. She had been vaccinated regularly with no apparent ill effects and there were no other health problems, only a behavioral inconvenience.

Coco had lived with three other neutered bitches all her life and was friendly towards them. However, she would frequently mount any one of them, and if they protested run off and hide.

Originally her owner had planned to breed with her and so she was not neutered as a puppy. Her seasons had been regular but abnormally mild. Neutering at around 2.5 years of age did nothing to change the sexual behavior. She was wary of other dogs, and if approached would initially “freeze” and escape at the first opportunity. If she finally got to know another dog, she was friendly and playful. Her appetite was steady, preferring dry food, and not drinking as much as her companions. She liked cuddles from the owner. She was tolerant of heat but was happy to let others be near the fire.
 She was given Pulsatilla 200C for three days, with Cicuta virosa M in case of an attack. She was re-presented two months later, having had a mild fit. The Cicuta had not been given. The owner reported she was “more like her old self”. Pulsatilla200C was repeated. She has had no more fits and is now more confident with other dogs.

Zeberdee was a seven-year-old Sheltie, an epileptic for three years. There was no known family history of epilepsy. The first fit had occurred within 24 hours of a booster vaccination. His only other health problem was chronic eczema and he had kennel cough. He was on a high dose of phenobarbitone four times daily, but the fits still occurred every three weeks. During them he would hyperventilate, be on his side with legs thrashing about in an in-coordinated manner, salivate profusely, and pass urine.

There was usually one scream before the fit. All but the last fit had occurred at night. He recovered in about an hour and was then ravenously hungry, being very sensitive to noise during that time. His owner had given Bufo 30C on two occasion’s and this had increased the intervals to five and eight weeks respectively, but he had now reverted to his three weekly pattern.
 He was described as friendly to dogs and ladies but wary of men. He liked to play but disliked being cuddled. He was frightened of thunder, fireworks, and very wary in a crowd. He disliked the fire and preferred to be outside in all weathers, but would lie in the sun. His appetite was always good, his thirst normal, and he did not suffer from flatulence.

Treatment was started with a combined vaccine nosode 30C, for four days. This was followed by Lycopodium 200C for two days. There were then two mild fits, each lasting about one minute, and each six weeks apart. He was reported as being more confident with men but otherwise unchanged. Lycopodium 200 was repeated. There were no more fits for five months, then one violent fit daily for three days. Hyoscyamus 30C stopped the sequence and Lycopodium M was given for one day. There have now been no fits for over a year and his medication has been withdrawn. His eczema has also improved.
Some of the most useful remedies in the epileptic situation

Aconite
 Useful for both attendant and patient! The sudden onset fits the picture, and fear is sometimes seen just prior to the fit.

Belladonna
 Another remedy where suddenness is a feature, together with the violence of the convulsions. There is great sensitivity during the fit, and the slightest external stimulus will keep it going. The attack usually involves a single fit rather than a cluster. As it is the acute of Calc carb, it is often of use where that is the indicated constitutional remedy.

Bufo
 This has the reputation of the keynote of fits occurring during sleep. In actual fact, the link is to night and sleep combined. The other feature is worse in a warm room. There is often a howl at the start of the fit.

Cicuta virosa
 A distinctive feature here is that during the spasms the head is thrown back and to the side, so that the muzzle rests on the shoulder blade facing towards the tail.

Cocculus
 A very useful remedy, its connection with vertigo gives it its place in this context.

Hyoscyamus
 Related to Belladonna and Stramonium, this is also an excellent “local” remedy. Its picture is characterized by excessive movements of the face, both prior to a fit and at other times.

Kali brom
 As Potassium bromide this is used as a conventional anti-convulsant, and it is also employed as a homeopathic remedy. The timing of the fits is often linked to oestrus, and there is marked excitement before they start.

Nux vom
 Together with Ignatia the main ingredient is strychnine. These two, together with the remedy Strychninum have a role to play.

Courtesy to the Author

Monday, August 6, 2012

Efficacy of macrocyclic lactone treatments in sheep in the UK

rssVeterinary Record 2012;170:653 doi:10.1136/vr.e4289 Lesley Stubbings on behalf of SCOPS

3 Fullers Close, Aldwincle, Kettering, Northamptonshire NN14 3UUe-mail: lesley{at}lssc.fsnet.co.ukVERY few data exist on the prevalence of macrocyclic lactone (ML) resistance in the UK. This is due in part to the lack of testing carried out, but is exacerbated by the lack of an in vitro test, which means that the only way we can reliably confirm resistance is by conducting a faecal egg count reduction test (FECRT).

In support of previous work carried out by SCOPS (Sustainable Control of …

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Advancing the clinical care of rabbits

Veterinary Record 2012;170:634 doi:10.1136/vr.e4228 A NEW three-year scholarship for a residency in rabbit and exotic animal medicine and surgery has been created at the Royal (Dick) School of Veterinary Studies (R[D]SVS) in Edinburgh. The post, which is jointly funded …


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